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Design

Key Technology

Hsp70 was identified as a novel tumor-specific target structure which acts as a recognition signal for Natural Killer (NK) cells by the company's co-founders. Hsp70-expression has been detected on various tumor entities (e.g. lung and colorectal carcinomas, leukemias) and metastases, but not on healthy tissues.

Cancer Percentage of patients in whom Hsp70 is expressed on the membrane of their tumors
Non small cell lung carcinoma (NSCLC) 50-75%
Colorectal carcinoma 40-55%
Breast carcinoma 45-60%
Pancreas carcinoma 50-70%
Head/neck carcinoma 60-80%
Leukemia 70-90%
Melanoma 50-65%
Non-Hodgkin´s Lymphoma 40-60%
Renal cell carcinoma 50-60%